TargetMol

Oligomycin A

Product Code:
 
TAR-T6323
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T6323-25mg25mgEnquire
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TAR-T6323-50mg50mgEnquire
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TAR-T6323-1mg1mg£122.00
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TAR-T6323-2mg2mg£141.00
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TAR-T6323-5mg5mg£168.00
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TAR-T6323-1mL1 mL * 10 mM (in DMSO)£180.00
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TAR-T6323-10mg10mg£229.00
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Further Information

Bioactivity:
Oligomycin A is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria.
CAS:
579-13-5
Formula:
C45H74O11
Molecular Weight:
791.076
Pathway:
Microbiology/Virology; Membrane transporter/Ion channel
Purity:
0.9986
SMILES:
[H][C@]12CC[C@@H](CC)C=CC=CC[C@@H](C)[C@H](O)[C@@](C)(O)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C=CC(=O)O[C@]([H])([C@@H]1C)[C@H](C)[C@@]1(CC[C@H](C)[C@H](C[C@@H](C)O)O1)O2
Target:
ATPase; Antibiotic; Antifungal

References

Hao W, et al. J Biol Chem, 2010, 285(17), 12647-12654. Jiang X C, Tu F H, Wei L Y, et al. Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer. Journal of Medicinal Chemistry. 2022 Roesch A, et al. Cancer Cell, 2013, 23(6), 811-825. Jastroch M, et al. Essays Biochem. 2010;47:53-67. Shchepina LA, et al. Oncogene, 2002, 21(53):8149-8157.