TargetMol

AZ960

Product Code:
 
TAR-T6309
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6309-1mg1mg£124.00
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TAR-T6309-2mg2mg£136.00
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TAR-T6309-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T6309-5mg5mg£172.00
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TAR-T6309-10mg10mg£237.00
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TAR-T6309-25mg25mg£377.00
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Quantity:
TAR-T6309-50mg50mg£527.00
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This product comes from: United States.
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Further Information

Bioactivity:
AZ 960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
CAS:
905586-69-8
Formula:
C18H16F2N6
Molecular Weight:
354.365
Pathway:
JAK/STAT signaling; Apoptosis; Chromatin/Epigenetic; Microbiology/Virology; Angiogenesis; Stem Cells
Purity:
0.9602
SMILES:
C[C@H](Nc1nc(Nc2cc(C)[nH]n2)c(F)cc1C#N)c1ccc(F)cc1
Target:
Apoptosis; Virus Protease; JAK; Parasite

References

Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond?Blackfan anemia[J]. Cell Death & Disease. 2020, 11(2): 1-11. Gozgit JM, et al. J Biol Chem. 2008, 283(47), 32334-32343. Ikezoe T, et al. Int J Cancer. 2011, 129(10), 2512-2521. Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond?Blackfan anemia. Cell Death & Disease. 2020, 11(2): 1-11 Yang J, et al. Mol Cancer Ther. 2010, 9(12), 3386-3395.