TargetMol

NVP-BSK805 2HCl (1092499-93-8(free base))

Product Code:
 
TAR-T6294
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6294-1mg1mg£113.00
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TAR-T6294-2mg2mg£147.00
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TAR-T6294-5mg5mg£213.00
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TAR-T6294-10mg10mg£267.00
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TAR-T6294-1mL1 mL * 10 mM (in DMSO)£390.00
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TAR-T6294-25mg25mg£436.00
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TAR-T6294-50mg50mg£586.00
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TAR-T6294-100mg100mg£809.00
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TAR-T6294-500mg500mg£1,564.00
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Further Information

Bioactivity:
NVP-BSK805 2HCl(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
CAS:
T6294
Formula:
C27H28F2N6O?2HCl
Molecular Weight:
563.47
Pathway:
Stem Cells; Tyrosine Kinase/Adaptors; Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling
Purity:
0.98
SMILES:
Cl.Cl.Fc1cc(cc(F)c1CN1CCOCC1)-c1cccc2ncc(nc12)-c1cnn(c1)C1CCNCC1
Target:
Tyrosine Kinases; JAK

References

Rubert J, et al. BMC Cancer, 2011, Jan(19), 11-24. Baffert F, et al. Mol Cancer Ther, 2010, 9(7), 1945-1955.