TargetMol

Nutlin-3a

Product Code:
 
TAR-T6023
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6023-1mg1mg£107.00
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TAR-T6023-2mg2mg£122.00
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TAR-T6023-5mg5mg£148.00
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TAR-T6023-1mL1 mL * 10 mM (in DMSO)£181.00
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TAR-T6023-10mg10mg£205.00
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TAR-T6023-25mg25mg£297.00
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Quantity:
TAR-T6023-50mg50mg£406.00
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Quantity:
TAR-T6023-100mg100mg£567.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Nutlin-3a, the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.
CAS:
675576-98-4
Formula:
C30H30Cl2N4O4
Molecular Weight:
581.49
Pathway:
Apoptosis; Ubiquitination; Autophagy
Purity:
0.9873
SMILES:
COc1ccc(C2=N[C@H]([C@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
Target:
Apoptosis; E1/E2/E3 Enzyme; Autophagy

References

Tovar C, et al. Proc Natl Acad Sci U S A, 2006, 103(6), 1888-1893. Ohnstad HO, et al. BMC Cancer, 2011, 11(211), 1-11. Vassilev LT, et al. Science, 2004, 303(5659), 844-848.