TargetMol

MMP-12 Inhibitor

Product Code:
 
TAR-T60083
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T60083-1mg1mg£227.00
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Quantity:
TAR-T60083-5mg5mg£430.00
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TAR-T60083-10mg10mg£613.00
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TAR-T60083-25mg25mg£997.00
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Quantity:
TAR-T60083-50mg50mg£1,459.00
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Quantity:
TAR-T60083-100mg100mg£2,155.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
CAS:
1258003-93-8
Formula:
C19H20N2O7S
Molecular Weight:
420.44
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
N(C(OC)=O)C=1C=C2C=3C(OC2=CC1)=CC(S(N[C@H](C(C)C)C(O)=O)(=O)=O)=CC3
Target:
MMP

References

Wei Li, et al. A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408). Journal of Medicinal Chemistry 2009 52 (7), 1799-1802