TargetMol

KIF18A-IN-2

Product Code:
 
TAR-T60026
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T60026-1mg1mg£226.00
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TAR-T60026-5mg5mg£462.00
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TAR-T60026-1mL1 mL * 10 mM (in DMSO)£545.00
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TAR-T60026-10mg10mg£646.00
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TAR-T60026-25mg25mg£970.00
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TAR-T60026-50mg50mg£1,259.00
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Quantity:
TAR-T60026-100mg100mg£1,661.00
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Quantity:
TAR-T60026-500mg500mg£3,259.00
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This product comes from: United States.
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Further Information

Bioactivity:
KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.
CAS:
2600559-20-2
Formula:
C25H34N4O5S2
Molecular Weight:
534.69
Pathway:
Cytoskeletal Signaling
Purity:
0.9905
SMILES:
O=C(NC1=CC=CC(=C1)S(=O)(=O)NC(C)(C)C)C2=CC=C(C=C2N3CCC4(CC3)CC4)NS(=O)(=O)C
Target:
Microtubule Associated

References

Tamayo NA, et al. Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe. J Med Chem. 2022;65(6):4972-4990.