TargetMol

Moslosooflavone

Product Code:
 
TAR-T5773
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5773-1mg1mg£138.00
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TAR-T5773-5mg5mg£228.00
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TAR-T5773-10mg10mg£307.00
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TAR-T5773-25mg25mg£470.00
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TAR-T5773-50mg50mg£651.00
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TAR-T5773-100mg100mg£863.00
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Quantity:
TAR-T5773-500mg500mg£1,661.00
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Further Information

Bioactivity:
5-hydroxy-7,8-dimethoxyflavone has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages.
CAS:
3570-62-5
Formula:
C17H14O5
Molecular Weight:
298.294
Pathway:
NF-κb; Immunology/Inflammation; Metabolism
Purity:
0.98
SMILES:
COc1cc(O)c2c(oc(cc2=O)-c2ccccc2)c1OC
Target:
NF-κB; Reactive Oxygen Species

References

Jing L L , He L , Fan P C , et al. [Chemical Constituents with Anti-hypoxia Activity from Saussurea involucrata][J]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, 38(1):89-92. Chao W W , Kuo Y H , Lin B F . Anti-inflammatory Activity of New Compounds from Andrographis paniculata by NF-??B Transactivation Inhibition[J]. Journal of Agricultural and Food Chemistry, 2010, 58(4):2505-2512.