TargetMol

ZD-4190

Product Code:
 
TAR-T5475
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5475-1mg1mg£189.00
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TAR-T5475-2mg2mg£243.00
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TAR-T5475-5mg5mg£329.00
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TAR-T5475-1mL1 mL * 10 mM (in DMSO)£332.00
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TAR-T5475-10mg10mg£483.00
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TAR-T5475-25mg25mg£743.00
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Quantity:
TAR-T5475-50mg50mg£1,002.00
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Quantity:
TAR-T5475-100mg100mg£1,324.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
ZD-4190 is a inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling, used for the treatment of cancer.
CAS:
413599-62-9
Formula:
C19H16BrFN6O2
Molecular Weight:
459.279
Pathway:
Tyrosine Kinase/Adaptors; JAK/STAT signaling; Angiogenesis
Purity:
0.9942
SMILES:
COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCn1ccnn1
Target:
EGFR; VEGFR

References

Yang M, et al. PET imaging of early response to the tyrosine kinase inhibitor ZD4190. Eur J Nucl Med Mol Imaging. 2011 Jul;38(7):1237-47. doi: 10.1007/s00259-011-1742-z. Epub 2011 Mar 1.