TargetMol

PQR620

Product Code:
 
TAR-T5472
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5472-1mg1mg£148.00
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TAR-T5472-1mL1 mL * 10 mM (in DMSO)£270.00
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TAR-T5472-5mg5mg£275.00
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TAR-T5472-10mg10mg£367.00
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TAR-T5472-25mg25mg£570.00
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TAR-T5472-50mg50mg£781.00
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Quantity:
TAR-T5472-100mg100mg£1,026.00
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This product comes from: United States.
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Further Information

Bioactivity:
PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC1/2.
CAS:
1927857-56-4
Formula:
C21H25F2N7O2
Molecular Weight:
445.475
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9811
SMILES:
[H][C@]12CC[C@]([H])(COC1)N2c1nc(nc(n1)-c1cnc(N)cc1C(F)F)N1[C@@]2([H])CC[C@]1([H])COC2
Target:
mTOR

References

Florent Beaufils, et al. Abstract 1336: Structure-activity relationship studies, synthesis, and biological evaluation of PQR620, a highly potent and selective mTORC1/2 inhibitor. Cancer Research; 2016 Apr 16-20.