TargetMol

KKL-35

Product Code:
 
TAR-T5331
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5331-1mg1mg£128.00
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TAR-T5331-5mg5mg£214.00
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TAR-T5331-1mL1 mL * 10 mM (in DMSO)£222.00
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TAR-T5331-10mg10mg£290.00
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TAR-T5331-25mg25mg£442.00
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TAR-T5331-50mg50mg£607.00
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Quantity:
TAR-T5331-100mg100mg£820.00
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This product comes from: United States.
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Further Information

Bioactivity:
KKL-35 is an inhibitor of trans-translation (IC50: 0.9 μM) with broad-spectrum antibiotic activity.
CAS:
865285-29-6
Formula:
C15H9ClFN3O2
Molecular Weight:
317.7
Pathway:
Microbiology/Virology
Purity:
0.9966
SMILES:
Fc1ccc(cc1)-c1nnc(NC(=O)c2ccc(Cl)cc2)o1
Target:
Antibacterial

References

1. Ramadoss NS, et al. Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10282-7. Brunel R, et al. KKL-35 Exhibits Potent Antibiotic Activity against Legionella Species Independently of trans-Translation Inhibition. Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01459-17.