TargetMol

BAI1

Product Code:
 
TAR-T5210
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5210-1mg1mg£98.00
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TAR-T5210-2mg2mg£109.00
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TAR-T5210-5mg5mg£135.00
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TAR-T5210-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T5210-10mg10mg£173.00
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TAR-T5210-25mg25mg£274.00
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TAR-T5210-50mg50mg£442.00
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TAR-T5210-100mg100mg£618.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
CAS:
335165-68-9
Formula:
C19H21Br2N3O
Molecular Weight:
467.2
Pathway:
Apoptosis
Purity:
0.9958
SMILES:
BrC1=CC=C2C(=C1)C=3C=C(Br)C=CC3N2CC(O)CN4CCNCC4
Target:
Apoptosis; BCL

References

Bombrun A, et al. 3,6-dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. J Med Chem. 2003 Oct 9;46(21):4365-8. Garner TP, et al. Small-molecule allosteric inhibitors of BAX. Nat Chem Biol. 2019 Apr;15(4):322-330.