TargetMol

3-Deoxyaconitine

Product Code:
 
TAR-T4S1876
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S1876-1mg1mg£107.00
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TAR-T4S1876-5mg5mg£149.00
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TAR-T4S1876-1mL1 mL * 10 mM (in DMSO)£159.00
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TAR-T4S1876-10mg10mg£185.00
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TAR-T4S1876-25mg25mg£262.00
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TAR-T4S1876-50mg50mg£353.00
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Further Information

Bioactivity:
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.
CAS:
3175-95-9
Formula:
C34H47NO10
Molecular Weight:
629.747
Pathway:
Membrane transporter/Ion channel
Purity:
0.9976
SMILES:
CCN1C[C@]2(COC)CC[C@H](OC)[C@@]34[C@@H]5C[C@@]6(O)[C@H](OC(=O)c7ccccc7)[C@@H]5[C@@](OC(C)=O)([C@@H]([C@H](OC)[C@H]23)C14)[C@@H](O)[C@@H]6OC
Target:
Sodium Channel

References

Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010) Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010),