TargetMol

Berberrubine chloride

Product Code:
 
TAR-T4S0795
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S0795-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T4S0795-20mg20mg£175.00
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Further Information

Bioactivity:
1. Berberrubine has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.
CAS:
15401-69-1
Formula:
C19H16ClNO4
Molecular Weight:
357.79
Pathway:
Immunology/Inflammation
Purity:
0.9781
SMILES:
[Cl-].COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1O
Target:
IL Receptor

References

Cui H S , Hayasaka S , Zhang X Y , et al. Effect of berberrubine on interleukin-8 and monocyte chemotactic protein-1 expression in human retinal pigment epithelial cell line[J]. Life Sciences, 2006, 79(10):0-956. He X, Cui J, Ma H, et al.Berberrubine is a novel and selective IMPDH2 inhibitor that impairs the growth of colorectal cancer.Biochemical Pharmacology.2023: 115868.