TargetMol

TA-02

Product Code:
 
TAR-T4646
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4646-5mg5mg£115.00
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Quantity:
TAR-T4646-1mL1 mL * 10 mM (in DMSO)£119.00
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Quantity:
TAR-T4646-10mg10mg£142.00
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TAR-T4646-25mg25mg£213.00
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Quantity:
TAR-T4646-50mg50mg£289.00
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Quantity:
TAR-T4646-100mg100mg£414.00
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Quantity:
TAR-T4646-500mg500mg£849.00
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This product comes from: United States.
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Further Information

Bioactivity:
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
CAS:
1784751-19-4
Formula:
C20H13F2N3
Molecular Weight:
333.342
Pathway:
MAPK; Autophagy
Purity:
0.9936
SMILES:
Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccccc1F
Target:
p38 MAPK; Autophagy

References

Filip LACO, et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO 201519579 A1. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.