TargetMol

Lucanthone

Product Code:
 
TAR-T4569
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4569-1mg1mg£111.00
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TAR-T4569-5mg5mg£173.00
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TAR-T4569-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T4569-10mg10mg£230.00
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TAR-T4569-25mg25mg£409.00
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TAR-T4569-50mg50mg£575.00
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TAR-T4569-100mg100mg£788.00
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This product comes from: United States.
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Further Information

Bioactivity:
Lucanthone is an inhibitor of Apurinic endonuclease-1 (APE-1).
CAS:
479-50-5
Formula:
C20H24N2OS
Molecular Weight:
340.49
Pathway:
Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9991
SMILES:
CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12
Target:
DNA/RNA Synthesis; Autophagy

References

Carew JS,etal.Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis.J Biol Chem. 2011 Feb 25;286(8):6602-13. Chowdhury SM,etal.Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme.Nanomedicine. 2015 Jan;11(1):109-18.