TargetMol

LM22B-10

Product Code:
 
TAR-T4496
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T4496-1mg1mg£114.00
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TAR-T4496-2mg2mg£138.00
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TAR-T4496-5mg5mg£173.00
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TAR-T4496-1mL1 mL * 10 mM (in DMSO)£179.00
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TAR-T4496-10mg10mg£244.00
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TAR-T4496-25mg25mg£470.00
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TAR-T4496-50mg50mg£670.00
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TAR-T4496-100mg100mg£914.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and AKT activation in vitro and in vivo.
CAS:
342777-54-2
Formula:
C27H33ClN2O4
Molecular Weight:
485.02
Pathway:
MAPK; PI3K/Akt/mTOR signaling; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Purity:
0.9913
SMILES:
OCCN(CCO)c1ccc(cc1)C(c1ccc(Cl)cc1)c1ccc(cc1)N(CCO)CCO
Target:
ERK; Trk receptor; Akt

References

Yang T, et al. A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth. Neuropharmacology. 2016 Nov;110(Pt A):343-61.