TargetMol

Asunaprevir

Product Code:
 
TAR-T4474
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T4474-1mg1mg£109.00
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TAR-T4474-2mg2mg£125.00
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TAR-T4474-5mg5mg£161.00
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TAR-T4474-1mL1 mL * 10 mM (in DMSO)£217.00
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TAR-T4474-10mg10mg£222.00
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TAR-T4474-25mg25mg£370.00
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Quantity:
TAR-T4474-50mg50mg£528.00
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TAR-T4474-100mg100mg£728.00
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Quantity:
TAR-T4474-500mg500mg£1,428.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
CAS:
630420-16-5
Formula:
C35H46ClN5O9S
Molecular Weight:
748.29
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.9992
SMILES:
COc1cnc(O[C@@H]2C[C@H](N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)N[C@@]2(C[C@H]2C=C)C(=O)NS(=O)(=O)C2CC2)c2cc(Cl)ccc12
Target:
HCV Protease; SARS-CoV

References

Pelosi LA, et al. Effect on HCV Replication by Combinations of Direct Acting Antivirals Including NS5A Inhibitor Daclatasvir. Antimicrob Agents Chemother. 2012 Jul 30. McPhee F, et al. Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032). Antimicrob Agents Chemother. 2012 Aug 6. Pasquinelli C, et al. Single- and multiple-ascending-dose studies of the NS3 protease inhibitor asunaprevir in subjects with or without chronic hepatitis C. Antimicrob Agents Chemother. 2012 Apr;56(4):1838-44. McPhee F, et al. Resistance analysis of the hepatitis C virus NS3 protease inhibitor asunaprevir. Antimicrob Agents Chemother. 2012 Jul;56(7):3670-81.