TargetMol

TLR7 agonist 2

Product Code:
 
TAR-T4258
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4258-1mg1mg£198.00
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TAR-T4258-2mg2mg£274.00
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TAR-T4258-1mL1 mL * 10 mM (in DMSO)£380.00
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TAR-T4258-5mg5mg£490.00
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TAR-T4258-10mg10mg£677.00
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TAR-T4258-25mg25mg£1,010.00
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TAR-T4258-50mg50mg£1,340.00
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TAR-T4258-100mg100mg£1,781.00
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Further Information

Bioactivity:
TLR7-agonist-1 is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).
CAS:
1642857-69-9
Formula:
C17H16N6O2
Molecular Weight:
336.355
Pathway:
Immunology/Inflammation
Purity:
0.984
SMILES:
Cc1cc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)no1
Target:
TLR

References

Lu J, Zhong X, Guo C, et al.TLR7-MyD88-DC-CXCL16 axis results neutrophil activation to elicit inflammatory response in pustular psoriasis.Cell Death & Disease.2023, 14(5): 1-13. McGowan DC, et al. Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B. J Med Chem. 2017 Jul 27;60(14):6137-6151.