TargetMol

SJ6986

Product Code:
 
TAR-T41257
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T41257-5mg5mg£109.00
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Quantity:
TAR-T41257-1mL1 mL * 10 mM (in DMSO)£114.00
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Quantity:
TAR-T41257-10mg10mg£133.00
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Quantity:
TAR-T41257-50mg50mg£277.00
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Quantity:
TAR-T41257-100mg100mg£389.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
SJ6986 is a chemical probe for studying the role of GSPT1/2 in vitro and in vivo. SJ6986 supports the utility of a diverse library of CRBN binders in the pursuit of targeting undruggable oncoproteins.
CAS:
2765625-93-0
Formula:
C20H14F3N3O7S
Molecular Weight:
497.4
Purity:
0.9945
SMILES:
O=C(N1)CCC(N2C(C(C=C(NS(C3=C(OC(F)(F)F)C=CC=C3)(=O)=O)C=C4)=C4C2=O)=O)C1=O

References

Nishiguchi G, et al. Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators. J Med Chem. 2021 Jun 10;64(11):7296-7311.