TargetMol

S 38093

Product Code:
 
TAR-T4099
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4099-1mg1mg£102.00
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TAR-T4099-2mg2mg£114.00
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TAR-T4099-5mg5mg£135.00
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TAR-T4099-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T4099-10mg10mg£168.00
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TAR-T4099-25mg25mg£249.00
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TAR-T4099-50mg50mg£367.00
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TAR-T4099-100mg100mg£542.00
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Further Information

Bioactivity:
S-38093 is a brain-penetrant antagonist of the H3 receptor (Ki: 8.8/1.44/1.2 μM, for rat/mouse/human).
CAS:
862896-30-8
Formula:
C17H24N2O2
Molecular Weight:
288.391
Pathway:
Neuroscience; Immunology/Inflammation; GPCR/G Protein
Purity:
0.9998
SMILES:
NC(=O)c1ccc(OCCCN2CC3CCCC3C2)cc1
Target:
Histamine Receptor

References

Guilloux JP, et al. S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Sci Rep. 2017 Feb 20;7:42946. Sors A, et al. Mechanistic characterization of S 38093, a novel inverse agonist at histamine H3 receptors. Eur J Pharmacol. 2017 May 15;803:11-23