TargetMol

BMS-986235

Product Code:
 
TAR-T39789
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39789-1mg1mg£189.00
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TAR-T39789-5mg5mg£369.00
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TAR-T39789-1mL1 mL * 10 mM (in DMSO)£389.00
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TAR-T39789-10mg10mg£517.00
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TAR-T39789-25mg25mg£790.00
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TAR-T39789-50mg50mg£1,050.00
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Quantity:
TAR-T39789-100mg100mg£1,396.00
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Further Information

Bioactivity:
BMS-986235 is a selective and orally active agonist of formyl peptide receptor 2 (FPR2) with EC50s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 can be used in studies about the prevention of heart failure.
CAS:
2253947-47-4
Formula:
C18H17F2N3O3
Molecular Weight:
361.34
Purity:
0.9965
SMILES:
O=C(NC=1C=CC=CC1)NC2C(=O)NCC2C=3C(F)=CC(OC)=CC3F

References

Asahina Y, et al. Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure [published online ahead of print, 2020 May 24]. J Med Chem. 2020;10.1021/acs.jmedchem.9b02101.