TargetMol

beta-Eudesmol

Product Code:
 
TAR-T3865
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3865-1mg1mg£122.00
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TAR-T3865-5mg5mg£189.00
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TAR-T3865-1mL1 mL * 10 mM (in DMSO)£197.00
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TAR-T3865-10mg10mg£254.00
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TAR-T3865-25mg25mg£383.00
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TAR-T3865-50mg50mg£531.00
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Further Information

Bioactivity:
β-Eudesmol is a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). It is a sesquiterpene that has been found in a variety of plants, including Cannabis, and has diverse biological activities.
CAS:
473-15-4
Formula:
C15H26O
Molecular Weight:
222.372
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.9985
SMILES:
CC(C)(O)[C@@H]1CC[C@@]2(C)CCCC(=C)[C@@H]2C1
Target:
TRP/TRPV Channel; AChR

References

Ohara K, et al. ?-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system. Sci Rep. 2017 Nov 17;7(1):15785. Ma E L, et al. Beta-eudesmol suppresses tumour growth through inhibition of tumour neovascularisation and tumour cell proliferation.[J]. Journal of Asian Natural Products Research, 2008, 10(2):159-167. Elzinga S, et al. Cannabinoids and Terpenes as Chemotaxonomic Markers in Cannabis[J]. Natural Products Chemistry & Research, 2015, 3. Kimura M, et al. Mechanism of the blocking action of beta-eudesmol on the nicotinic acetylcholine receptor channel in mouse skeletal muscles[J]. Neuropharmacology, 1991, 30(8):835-41. Ohara K, et al. Identification of Significant Amino Acids in Multiple Transmembrane Domains of Human Transient Receptor Potential Ankyrin 1 (TRPA1) for Activation by Eudesmol, an Oxygenized Sesquiterpene in Hop Essential Oil.[J]. Journal of Biological Chemistry, 2015, 290(5):3161-3171.