TargetMol

Isoliquiritin apioside

Product Code:
 
TAR-T3860
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3860-1mg1mg£123.00
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TAR-T3860-5mg5mg£189.00
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TAR-T3860-10mg10mg£247.00
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TAR-T3860-1mL1 mL * 10 mM (in DMSO)£263.00
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TAR-T3860-25mg25mg£372.00
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TAR-T3860-50mg50mg£518.00
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Further Information

Bioactivity:
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells. Isoliquiritin apioside has marked potential to combat oxidative stress-induced genotoxicity.
CAS:
120926-46-7
Formula:
C26H30O13
Molecular Weight:
550.513
Pathway:
Proteases/Proteasome; MAPK; NF-κb
Purity:
0.9927
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(C=CC(=O)c3ccc(O)cc3O)cc2)[C@H](O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@@H](O)[C@@H]1O
Target:
MMP; p38 MAPK; NF-κB

References

Kaur P , Kaur S , Kumar N , et al. Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L.[J]. toxicology in vitro, 2009, 23(4):0-686. Kim A1, et al. Isoliquiritin Apioside Suppresses in vitro Invasiveness and Angiogenesis of Cancer Cells and Endothelial Cells.Front Pharmacol. 2018 Dec 10;9:1455.