TargetMol

Guselkumab

Product Code:
 
TAR-T38362
Product Group:
 
Primary Antibodies
Supplier:
 
TargetMol
Antibody Clonality:
 
Monoclonal
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38362-1mg1mg£604.00
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Quantity:
TAR-T38362-5mg5mg£1,934.00
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This product comes from: United States.
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Further Information

Bioactivity:
Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research[1].
CAS:
1350289-85-8
Formula:
N/A
Molecular Weight:
0
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
N/A
Target:
IL Receptor

References

Li L, et al. IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis. Int Immunopharmacol. 2020;89(Pt B):107008. International non-proprietary name: guselkumab Procedure No. EMEA/H/C/004271/0000par-public-assessment-report_en.pdf