TargetMol

Fuscin

Product Code:
 
TAR-T37714
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37714-1mg1mg£275.00
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TAR-T37714-5mg5mg£1,001.00
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Quantity:
TAR-T37714-10mg10mg£1,726.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 μM in a radioligand binding assay. Fuscin (20 μM) reduces the glutathione content of rat liver mitochondria to 28% of controls and inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations in a concentration-dependent manner. It competes with macrophage inflammatory protein 1α (MIP-1α) for binding to CCR5 chemokine receptors in vitro with an IC50 value of 21 μM.
CAS:
83-85-2
Formula:
C15H16O5
Molecular Weight:
276.3
Purity:
0.98
SMILES:
O=C1OC(C)C(C2=C1)=C(O)C(C3=C2CCC(C)(C)O3)=O