TargetMol

Dasatinib N-oxide

Product Code:
 
TAR-T37600
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T37600-5mg5mg£131.00
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TAR-T37600-10mg10mg£148.00
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TAR-T37600-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T37600-25mg25mg£202.00
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TAR-T37600-50mg50mg£262.00
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TAR-T37600-100mg100mg£354.00
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Further Information

Bioactivity:
Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib.It is also a potential impurity in commercial preparations of dasatinib[1][2].
CAS:
910297-52-8
Formula:
C22H26ClN7O3S
Molecular Weight:
504
Purity:
0.9985
SMILES:
OCCN(CCN1C2=CC(NC3=NC=C(C(NC4=C(Cl)C=CC=C4C)=O)S3)=NC(C)=N2)(CC1)=O

References

Plachk?, K., ?vec, F., and Nov?kov?, L. Ultra-high performance supercritical fluid chromatography in impurity control: Searching for generic screening approach. Anal. Chim. Acta 1039, 149-161 (2018). Christopher, L.J., Cui, D., Li, W., et al. Biotransformation of [14C]dasatinib: In vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab. Dispos. 36(7), 1341-1356 (2008).