TargetMol

4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt)

Product Code:
 
TAR-T37566
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T37566-1mg1mg£163.00
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TAR-T37566-5mg5mg£241.00
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TAR-T37566-10mg10mg£381.00
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This product comes from: United States.
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Further Information

Bioactivity:
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
CAS:
206443-06-3
Formula:
C16H19NaO11S
Molecular Weight:
442.37
Purity:
0.98
SMILES:
[NaH].Cc1cc(=O)oc2cc(O[C@@H]3O[C@H](COS(O)(=O)=O)[C@H](O)[C@H](O)[C@H]3O)ccc12