TargetMol

5-hydroxy-6-methoxy (S)-Duloxetine

Product Code:
 
TAR-T37211
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37211-1mg1mg£338.00
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Further Information

Bioactivity:
5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine . It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S)-Duloxetine binds to the serotonin (5-HT), norepinephrine, and dopamine transporters with Ki values of 266, 920, and 2,814 nM, respectively.
CAS:
741693-79-8
Formula:
C19H21NO3S
Molecular Weight:
343.4
Purity:
0.98
SMILES:
CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C(O)C(OC)=CC=C32