TargetMol

Concanamycin B

Product Code:
 
TAR-T36116
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36116-1mg1mg£1,593.00
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This product comes from: United States.
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Further Information

Bioactivity:
Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late endosomal transport. Concanamycin B interferes with bone resorption and maturation of CD8 T lymphocytes. It also prevents processing of major histocompatibility complex (MHC) class II precursors in human B cells, inhibiting the expression of MHC class II molecules on the cell surface.
CAS:
81552-33-2
Formula:
C45H73NO14
Molecular Weight:
852.072
Purity:
0.98
SMILES:
COC1C=CC=C(C)CC(C)C(O)C(C)C(O)C(C)C=C(C)C=C(OC)C(=O)OC1C(C)C(O)C(C)C1(O)CC(OC2CC(O)C(OC(N)=O)C(C)O2)C(C)C(O1)C=CC