TargetMol

Sematilide hydrochloride

Product Code:
 
TAR-T3574
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3574-1mg1mg£96.00
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TAR-T3574-2mg2mg£107.00
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TAR-T3574-5mg5mg£128.00
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TAR-T3574-1mL1 mL * 10 mM (in DMSO)£138.00
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TAR-T3574-10mg10mg£161.00
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TAR-T3574-25mg25mg£254.00
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TAR-T3574-50mg50mg£369.00
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TAR-T3574-100mg100mg£550.00
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This product comes from: United States.
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Further Information

Bioactivity:
Sematilide (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of refractoriness and action potential duration.
CAS:
101526-62-9
Formula:
C14H24ClN3O3S
Molecular Weight:
349.87
Pathway:
Membrane transporter/Ion channel
Purity:
0.9941
SMILES:
Cl.CCN(CC)CCNC(=O)c1ccc(NS(C)(=O)=O)cc1
Target:
Potassium Channel

References

Yoshida H,et al. Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model. Circ J. 2002 Aug;66(8):758-62.