TargetMol

MTP 131 acetate

Product Code:
 
TAR-T35689
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35689-1mg1mg£125.00
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TAR-T35689-2mg2mg£149.00
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TAR-T35689-5mg5mg£177.00
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TAR-T35689-10mg10mg£242.00
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TAR-T35689-25mg25mg£372.00
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Quantity:
TAR-T35689-50mg50mg£518.00
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Quantity:
TAR-T35689-100mg100mg£699.00
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Quantity:
TAR-T35689-500mg500mg£1,404.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
MTP 131 (acetate) is a small mitochondrially-targeted tetrapeptide.
CAS:
1334953-95-5
Formula:
C32H49N9O5?XC2H4O2
Molecular Weight:
639.8
Purity:
0.98
SMILES:
CC(C=C(C=C1C)O)=C1C[C@H](NC([C@H](N)CCCNC(N)=N)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=O.CC(O)=O

References

Chen M, et al. Protective effect of mitochondria?targeted peptide MTP?131 against oxidative stress?induced apoptosis in RGC?5 cells. Mol Med Rep. 2017 Apr;15(4):2179-2185. Miyamoto S, Zhang G, Hall D, Oates PJ, Maity S, Madesh M, Han X, Sharma K. Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney disease. J Biol Chem. 2020 May 22;295(21):7249-7260. doi: 10.1074/jbc.RA119.011110. Epub 2020 Apr 10. PMID: 32277051; PMCID: PMC7247302. Miyamoto, S., Zhang, G., Hall, D., et al.Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney diseaseJ. Biol. Chem.295(21)7249-7260(2020)