TargetMol

21-deacetyldeflazacort

Product Code:
 
TAR-T29328
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29328-1mg1mg£125.00
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TAR-T29328-5mg5mg£203.00
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TAR-T29328-1mL1 mL * 10 mM (in DMSO)£209.00
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TAR-T29328-10mg10mg£267.00
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TAR-T29328-25mg25mg£405.00
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TAR-T29328-50mg50mg£547.00
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Further Information

Bioactivity:
21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.
CAS:
13649-57-5
Formula:
C23H29NO5
Molecular Weight:
399.487
Purity:
0.9929
SMILES:
CC1=N[C@@]2([C@@H](C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C)O1)C(=O)CO

References

1. Omote M, et al. Acute effects of deflazacort and its metabolite 21-desacetyl-deflazacort on allergic reactions. Arzneimittelforschung. 1994 Feb;44(2):149-53. 2. Luzzani F, Gl?sser A. Differential binding in vitro to glucocorticoid receptors of deflazacort and prednisolone. Eur J Pharmacol. 1981 Dec 17;76(4):427-30. doi: 10.1016/0014-2999(81)90115-1. 3. Ifa DR, et al. Determination of 21-hydroxydeflazacort in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Application to bioequivalence study. J Mass Spectrom. 2000 Mar;35(3):440-5. 4. Reynolds DL, et al. Quantitative determination of 21-hydroxy-deflazacort in human plasma using gradient semi-microbore liquid chromatography. Biomed Chromatogr. 1994 Sep-Oct;8(5):230-5.