TargetMol

ZK118182 isopropyl ester

Product Code:
 
TAR-T29225
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
ZK118182 isopropyl ester is a PG analog with potent DP-agonist activity (EC50 = 16.5 nM) and high affinity for the DP receptor (Ki = 74 nM).
CAS:
154927-31-8
Formula:
C23H37ClO5
Molecular Weight:
428.99
Purity:
0.98
SMILES:
CC(C)OC(=O)COCC=C/CC1(C[C@H](O)C[C@H]1Cl)C=C[C@@H](O)C1CCCCC1

Documents

References

1. Sharif, N.A.,Williams, G.W.,Crider, J.Y., et al. Molecular pharmacology of the DP/EP2 class prostaglandin AL-6598 and quantitative autoradiographic visualization of DP and EP2 receptor sites in human eyes. Journal of Ocular Pharmacology and Therapeutics 20(6), 489-508 (2004). 2. Hellberg, M.R.,Conrow, R.E.,Sharif, N.A., et al. 3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents. Bioorganic & Medicinal Chemistry 10, 2031-2049 (2002).