TargetMol

Slingshot inhibitor D3

Product Code:
 
TAR-T28804
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28804-1mg1mg£109.00
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TAR-T28804-5mg5mg£161.00
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TAR-T28804-1mL1 mL * 10 mM (in DMSO)£171.00
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TAR-T28804-10mg10mg£229.00
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TAR-T28804-25mg25mg£414.00
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TAR-T28804-50mg50mg£584.00
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TAR-T28804-100mg100mg£785.00
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TAR-T28804-500mg500mg£1,540.00
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This product comes from: United States.
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Further Information

Bioactivity:
Slingshot inhibitor D3 is a potent inhibitor of the Protein Phosphatase Slingshot.
CAS:
1715076-35-9
Formula:
C25H19NO4S2
Molecular Weight:
461.55
Purity:
0.9953
SMILES:
Cc1ccccc1N1C(=S)SC(=C/c2ccc(OCc3ccc(cc3)C(O)=O)cc2)C1=O

References

1. Lee SY, Kim W, Lee YG, Kang HJ, Lee SH, Park SY, Min JK, Lee SR, Chung SJ. Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis. Pharmacol Res. 2017 May;119:422-430. doi: 10.1016/j.phrs.2017.03.003. Epub 2017 Mar 6. PubMed PMID: 28274853. 2. Bao Z, Han X, Chen F, Jia X, Zhao J, Zhang C, Yong C, Tian S, Zhou X, Han L. Evidence for the involvement of cofilin in Aspergillus fumigatus internalization into type II alveolar epithelial cells. BMC Microbiol. 2015 Aug 13;15:161. doi: 10.1186/s12866-015-0500-y. PubMed PMID: 26268695; PubMed Central PMCID: PMC4542120. 3. Wang Y, Kuramitsu Y, Kitagawa T, Baron B, Yoshino S, Maehara S, Maehara Y, Oka M, Nakamura K. Cofilin-phosphatase slingshot-1L (SSH1L) is over-expressed in pancreatic cancer (PC) and contributes to tumor cell migration. Cancer Lett. 2015 May 1;360(2):171-6. doi: 10.1016/j.canlet.2015.02.015. Epub 2015 Feb 12. PubMed PMID: 25684665. 4. Homma Y, Kanno S, Sasaki K, Nishita M, Yasui A, Asano T, Ohashi K, Mizuno K. Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation. J Biol Chem. 2014 Sep 19;289(38):26302-13. doi: 10.1074/jbc.M114.565945. Epub 2014 Aug 6. PubMed PMID: 25100728; PubMed Central PMCID: PMC4176240.