TargetMol

cjoc42

Product Code:
 
TAR-T27029
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T27029-1mg1mg£166.00
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TAR-T27029-5mg5mg£309.00
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TAR-T27029-1mL1 mL * 10 mM (in DMSO)£346.00
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TAR-T27029-10mg10mg£454.00
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TAR-T27029-25mg25mg£704.00
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TAR-T27029-50mg50mg£938.00
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Quantity:
TAR-T27029-100mg100mg£1,259.00
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Quantity:
TAR-T27029-500mg500mg£2,456.00
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This product comes from: United States.
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Further Information

Bioactivity:
cjoc42 is an inhibitor of gankyrin, an ankyrin-repeat oncoprotein whose overexpression has been implicated in the development of many cancer types. cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin, and it restores p53-dependent transcription and sensitivity to DNA damage
CAS:
2171519-89-2
Formula:
C20H21N3O5S
Molecular Weight:
415.46
Purity:
0.9854
SMILES:
O=C(OC)C1=CC=C(N2N=NC(CCCOS(=O)(C3=CC=C(C)C=C3)=O)=C2)C=C1

References

1. Chattopadhyay A, et al. Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell. Sci Rep. 2016;6:23732.