TargetMol

AT-130

Product Code:
 
TAR-T26674
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26674-1mg1mg£124.00
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TAR-T26674-5mg5mg£201.00
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TAR-T26674-1mL1 mL * 10 mM (in DMSO)£213.00
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TAR-T26674-10mg10mg£322.00
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TAR-T26674-25mg25mg£470.00
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TAR-T26674-50mg50mg£651.00
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TAR-T26674-100mg100mg£863.00
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This product comes from: United States.
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Further Information

Bioactivity:
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.
CAS:
211364-06-6
Formula:
C22H22BrN3O5
Molecular Weight:
488.338
Pathway:
DNA Damage/DNA Repair; Microbiology/Virology; Cell Cycle/Checkpoint
Purity:
0.9862
SMILES:
COc1ccccc1C(Br)=C(/NC(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)N1CCCCC1
Target:
HBV; DNA/RNA Synthesis

References

1. Feld JJ, Colledge D, Sozzi V, Edwards R, Littlejohn M, Locarnini SA. The phenylpropenamide derivative AT-130 blocks HBV replication at the level of viral RNA packaging. Antiviral Res. 2007 Nov;76(2):168-77. Epub 2007 Jul 24. PubMed PMID: 17709147.