TargetMol

Amuvatinib

Product Code:
 
TAR-T2516
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T2516-1mg1mg£106.00
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TAR-T2516-2mg2mg£120.00
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TAR-T2516-5mg5mg£145.00
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TAR-T2516-1mL1 mL * 10 mM (in DMSO)£152.00
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TAR-T2516-10mg10mg£191.00
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TAR-T2516-25mg25mg£291.00
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TAR-T2516-50mg50mg£425.00
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TAR-T2516-100mg100mg£517.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Amuvatinib is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
CAS:
850879-09-3
Formula:
C23H21N5O3S
Molecular Weight:
447.51
Pathway:
Apoptosis; DNA Damage/DNA Repair; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9954
SMILES:
S=C(NCc1ccc2OCOc2c1)N1CCN(CC1)c1ncnc2c3ccccc3oc12
Target:
Apoptosis; FLT; c-Met/HGFR; c-RET; DNA/RNA Synthesis; PDGFR; c-Kit

References

2. Hurley LH, et al. World Patent, WO/2005/037825. 3. Mahadevan D, et al. Oncogene, 2007, 26(27), 3909-3919. 4. Qi W, et al. BMC Cancer, 2009, 9, 142. 5. Welsh JW, et al. Radiat Oncol, 2009, 4, 69. 6. Han H W, Hahn S, Jeong H Y, et al. LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent[J]. Scientific reports. 2018 Oct 8;8(1):14969.