TargetMol

AKT-I-1

Product Code:
 
TAR-T25017
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T25017-1mg1mg£258.00
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Quantity:
TAR-T25017-5mg5mg£454.00
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TAR-T25017-10mg10mg£631.00
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TAR-T25017-25mg25mg£946.00
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Quantity:
TAR-T25017-50mg50mg£1,251.00
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Quantity:
TAR-T25017-100mg100mg£1,669.00
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This product comes from: United States.
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Further Information

Bioactivity:
AKT-I-1 is a selective and reversible inhibitor of Akt1.
CAS:
473382-39-7
Formula:
C22H30N6
Molecular Weight:
378.524
Pathway:
PI3K/Akt/mTOR signaling; Cytoskeletal Signaling
Purity:
0.98
SMILES:
CN(C)CC(C)(C)CNc1nn2c(nnc2cc1C1CCC1)-c1ccccc1
Target:
Akt

References

1. Zhang Q, et al. Autophagy prevention sensitizes AKTi-1/2-induced anti-hepatocellular carcinoma cell activity in vitro and in vivo. Biochem Biophys Res Commun. 2016 Nov 18;480(3):334-340. 2. Zhao QW, et al. Akt mediated phosphorylation of Oct4 is associated with the proliferation of stem like cancer cells. Oncol Rep. 2015 Apr;33(4):1621-9. 3. Yamaji M, et al. Novel ATP-competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells. Cancer Med. 2017 Nov;6(11):2646-2659. 4. Liebl D, et al. SopB-Mediated Recruitment of SNX18 Facilitates Salmonella Typhimurium Internalization by the Host Cell. Front Cell Infect Microbiol. 2017 Jun 15;7:257.