TargetMol

YM-750

Product Code:
 
TAR-T23550
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23550-1mg1mg£102.00
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TAR-T23550-5mg5mg£138.00
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TAR-T23550-1mL1 mL * 10 mM (in DMSO)£145.00
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TAR-T23550-10mg10mg£182.00
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TAR-T23550-25mg25mg£294.00
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TAR-T23550-50mg50mg£436.00
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Quantity:
TAR-T23550-100mg100mg£610.00
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This product comes from: United States.
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Further Information

Bioactivity:
YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
CAS:
138046-43-2
Formula:
C31H36N2O
Molecular Weight:
452.642
Pathway:
Metabolism
Purity:
0.9963
SMILES:
Cc1cc(C)c(NC(=O)N(Cc2ccc-3c(Cc4ccccc-34)c2)C2CCCCCC2)c(C)c1
Target:
Acyltransferase

References

1. Nagata Y, et al. N-[2-[N'-pentyl-(6,6-dimethyl-2,4-heptadiynyl)amino]ethyl]- (2-methyl-1-naphthylthio)acetamide (FY-087). A new acyl coenzyme a:cholesterol acyltransferase (ACAT) inhibitor of diet-induced atherosclerosis formation in mice. Biochem Pharmacol. 1995;49(5):643-651.