TargetMol

Tracazolate hydrochloride

Product Code:
 
TAR-T23470
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23470-2mg2mg£99.00
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TAR-T23470-5mg5mg£118.00
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TAR-T23470-10mg10mg£148.00
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TAR-T23470-25mg25mg£229.00
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TAR-T23470-50mg50mg£334.00
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TAR-T23470-100mg100mg£466.00
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Further Information

Bioactivity:
Tracazolate hydrochloride is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM.
CAS:
1135210-68-2
Formula:
C16H25ClN4O2
Molecular Weight:
340.85
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Cl.CCCCNc1c(C(=O)OCC)c(C)nc2n(CC)ncc12
Target:
GABA Receptor

References

1. N Zheleznova, et al. alpha1beta2delta, a silent GABAA?receptor: recruitment by tracazolate and neurosteroids. Br J Pharmacol. 2008 Mar;153(5):1062-71. 2. Sally-Anne Thompson, et al. Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors. Mol Pharmacol. 2002 Apr;61(4):861-9.