TargetMol

NNC 63-0532

Product Code:
 
TAR-T23074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23074-1mg1mg£169.00
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TAR-T23074-2mg2mg£220.00
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TAR-T23074-5mg5mg£294.00
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TAR-T23074-10mg10mg£336.00
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TAR-T23074-25mg25mg£519.00
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TAR-T23074-50mg50mg£702.00
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TAR-T23074-100mg100mg£970.00
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Further Information

Bioactivity:
NNC 63-0532 is a potentnociceptin receptor agonist, Ki=7.3 nM, EC50=305 nM.
CAS:
250685-44-0
Formula:
C27H29N3O3
Molecular Weight:
443.54
Pathway:
GPCR/G Protein; Endocrinology/Hormones; Neuroscience
Purity:
0.9875
SMILES:
O=C(OC)CN1C(=O)C2(N(C=3C=CC=CC3)C1)CCN(CC4=CC=CC=5C=CC=CC54)CC2
Target:
Opioid Receptor

References

1. Thomsen C, Hohlweg R. (8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4. 5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist. Br J Pharmacol. 2000 Nov;131(5):903-8. 2. Li H, et al. Roles of K+ and cation channels in ORL-1 receptor-mediated depression of neuronal excitability and epileptic activities in the medial entorhinal cortex. Neuropharmacology. 2019 Jun;151:144-158.