TargetMol

SB399885 HCl

Product Code:
 
TAR-T19669
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19669-1mg1mg£193.00
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TAR-T19669-2mg2mg£230.00
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TAR-T19669-5mg5mg£309.00
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TAR-T19669-1mL1 mL * 10 mM (in DMSO)£362.00
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TAR-T19669-10mg10mg£426.00
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TAR-T19669-25mg25mg£658.00
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TAR-T19669-50mg50mg£863.00
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TAR-T19669-100mg100mg£1,187.00
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This product comes from: United States.
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Further Information

Bioactivity:
SB 399885 hydrochloride is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively).
CAS:
402713-80-8
Formula:
C18H22Cl3N3O4S
Molecular Weight:
482.8
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9894
SMILES:
O=S(C1=CC=C(OC)C(N2CCNCC2)=C1)(NC3=CC(Cl)=CC(Cl)=C3OC)=O.[H]Cl
Target:
5-HT Receptor

References

1. Abraham R, Nirogi R, Shinde A, Benade VS. Therapeutic Potential of 5-HT6 Antagonist SB399885 in Traumatic Stress Disorder. Drug Res (Stuttg). 2015 Aug;65(8):442-5. doi: 10.1055/s-0034-1390418. Epub 2014 Oct 13. PubMed PMID: 25310249.