TargetMol

Pradefovir mesylate

Product Code:
 
TAR-T19526
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19526-1mg1mg£242.00
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TAR-T19526-5mg5mg£436.00
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TAR-T19526-10mg10mg£610.00
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TAR-T19526-25mg25mg£922.00
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TAR-T19526-50mg50mg£1,219.00
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Quantity:
TAR-T19526-100mg100mg£1,613.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pradefovir mesylate is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 μM.
CAS:
625095-61-6
Formula:
C18H23ClN5O7PS
Molecular Weight:
519.89
Pathway:
Metabolism
Purity:
0.98
SMILES:
CS(O)(=O)=O.Nc1ncnc2n(CCOC[P@@]3(=O)OCC[C@H](O3)c3cccc(Cl)c3)cnc12
Target:
P45

References

1. Lin CC, et al. Metabolic activation of Pradefovir by CYP3A4 and its potential as an inhibitor or inducer. Antimicrob Agents Chemother. 2006 Sep;50(9):2926-31. 2. Zhang Y, Shen L, Zhan Y, Xiao QQ, Yang J. Development and Validation of a Sensitive LC-MS-MS Method for the Determination of Adefovir in Human Serum and Urine: Application to a Clinical Pharmacokinetic Study. J Chromatogr Sci. 2016 Apr;54(4):507-15.