TargetMol

Cyclic ADP-?ribose

Product Code:
 
TAR-T19253
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19253-5mg5mg£850.00
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Quantity:
TAR-T19253-50mg50mg£1,661.00
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Quantity:
TAR-T19253-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release and extracellular influx caused by the opening of TRPM2 channels.
CAS:
119340-53-3
Formula:
C15H21N5O13P2
Molecular Weight:
541.303
Pathway:
Metabolism; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
[H][C@]12COP(O)(=O)OP(O)(=O)OC[C@@]3([H])O[C@]([H])([C@H](O)[C@@H]3O)n3cnc4n(cnc4c3=N)[C@]([H])(O1)[C@H](O)[C@@H]2O
Target:
Calcium Channel

References

1. Ribeiro JM, et al. Specific cyclic ADP-ribose phosphohydrolase obtained by mutagenic engineering of Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase. Sci Rep. 2018 Jan 18;8(1):1036.