TargetMol

WAY-204688

Product Code:
 
TAR-T17252
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17252-1mg1mg£389.00
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Quantity:
TAR-T17252-5mg5mg£731.00
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Quantity:
TAR-T17252-10mg10mg£978.00
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Quantity:
TAR-T17252-25mg25mg£1,428.00
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Quantity:
TAR-T17252-50mg50mg£1,910.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
WAY-204688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50 = 122 nM in HAECT-1 cells).
CAS:
796854-35-8
Formula:
C34H31F3N2O2
Molecular Weight:
556.62
Pathway:
Endocrinology/Hormones; NF-κb
Purity:
0.9912
SMILES:
[C@H]([C@](C(=O)N1CCC(CC1)C2=CC(C(F)(F)F)=CC=C2)(C#N)C)(C=3C4=C(C=CC3)C=CC=C4)C5=C(OC)C=CC=C5
Target:
Estrogen/progestogen Receptor; NF-κB

References

1. Caggiano TJ, et al. Estrogen receptor dependent inhibitors of NF-kappaB transcriptional activation-1 synthesis and biological evaluation of substituted 2-cyanopropanoic acid derivatives: pathway selective inhibitors of NF-kappaB, a potential treatment for rheumatoid arthritis. J Med Chem. 2007 Nov 1;50(22):5245-8.