TargetMol

(RS)-(Tetrazol-5-yl)glycine

Product Code:
 
TAR-T16801
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16801-5mg5mg£119.00
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TAR-T16801-10mg10mg£148.00
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TAR-T16801-25mg25mg£262.00
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TAR-T16801-50mg50mg£401.00
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Quantity:
TAR-T16801-100mg100mg£544.00
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Further Information

Bioactivity:
(RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D, and GluN1/GluN2A, respectively.
CAS:
138199-51-6
Formula:
C3H5N5O2
Molecular Weight:
143.106
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.95
SMILES:
NC(C(O)=O)c1nnn[nH]1
Target:
NMDAR; iGluR

References

1. Schoepp DD, et al. D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist. Eur J Pharmacol. 1991 Oct 15;203(2):237-43. 2. Vance KM, et al. Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors. Nat Commun. 2011;2:294. 3. Duncan GE, et al. Seizure responses and induction of Fos by the NMDA agonist (tetrazol-5-yl)glycine in a geneticmodel of NMDA receptor hypofunction. Brain Res. 2008 Jul 24;1221:41-8.