TargetMol

RK-287107

Product Code:
 
TAR-T16761
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16761-1mg1mg£148.00
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TAR-T16761-5mg5mg£229.00
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TAR-T16761-1mL1 mL * 10 mM (in DMSO)£252.00
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TAR-T16761-10mg10mg£322.00
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TAR-T16761-25mg25mg£544.00
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TAR-T16761-50mg50mg£755.00
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Quantity:
TAR-T16761-100mg100mg£1,010.00
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This product comes from: United States.
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Further Information

Bioactivity:
RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).
CAS:
2171386-10-8
Formula:
C22H26F2N4O2
Molecular Weight:
416.473
Pathway:
; Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9959
SMILES:
OCCN1CC2(CCN(CC2)c2nc3CCCCc3c(=O)[nH]2)c2c1cc(F)cc2F
Target:
PARP

References

1. Mizutani A, et al. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model. Cancer Sci. 2018 Dec;109(12):4003-4014.