TargetMol

Mericitabine

Product Code:
 
TAR-T16710
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T16710-1mg1mg£131.00
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TAR-T16710-5mg5mg£217.00
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TAR-T16710-1mL1 mL * 10 mM (in DMSO)£229.00
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TAR-T16710-10mg10mg£275.00
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TAR-T16710-25mg25mg£425.00
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TAR-T16710-50mg50mg£592.00
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TAR-T16710-100mg100mg£814.00
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TAR-T16710-500mg500mg£1,572.00
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This product comes from: United States.
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Further Information

Bioactivity:
Mericitabine is a nucleoside HCV NS5B polymerase inhibitor. It acts as an RNA chain terminator and prevents the elongation of RNA transcripts during replication.
CAS:
940908-79-2
Formula:
C18H26FN3O6
Molecular Weight:
399.419
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.9739
SMILES:
CC(C)C(=O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@](C)(F)[C@@H]1OC(=O)C(C)C
Target:
HCV Protease

References

1. Le Pogam S, et al. Characterization of HCV quasispecies dynamics upon short term dual-therapy with the HCV NS5B nucleoside polymerase inhibitor mericitabine and the NS3/4 protease inhibitor danoprevir. Antimicrob Agents Chemother. 2012 Nov;56(11):5494-5 2. Soriano V, et al. Directly acting antivirals against hepatitis C virus. J Antimicrob Chemother. 2011 Aug;66(8):1673-86 3. Guedj J, et al. Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128). Hepatology. 2012 Apr;55(4):1030-7.