TargetMol

Maxacalcitol

Product Code:
 
TAR-T16015
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16015-1mg1mg£148.00
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TAR-T16015-5mg5mg£362.00
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TAR-T16015-1mL1 mL * 10 mM (in DMSO)£405.00
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TAR-T16015-10mg10mg£523.00
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TAR-T16015-25mg25mg£970.00
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TAR-T16015-50mg50mg£1,508.00
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This product comes from: United States.
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Further Information

Bioactivity:
Maxacalcitol is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.
CAS:
103909-75-7
Formula:
C26H42O4
Molecular Weight:
418.618
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@H](C)OCCC(C)(C)O)[C@@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C

References

1. Karashima T, et al. Successful Treatment of Bowen's Disease with Topical Maxacalcitol.Acta Derm Venereol. 2012 Jan 26. 2. Monier-Faugere, et al. 22-Oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. Kidney Int. (1999)55 821. 3. Inoue K, et al. Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.Lab Invest. 2012 Aug 27. 4. Barroga, et al. Inhibitory effects of 22-oxa-calcitriol and all-trans retinoic acid on the growth of a canine osteosarcoma derived cell-line in vivo and its pulmonary metastasis in vivo. Res.Vet.Sci. (2000)68 79.