TargetMol

MA-0204

Product Code:
 
TAR-T15945
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T15945-1mg1mg£189.00
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TAR-T15945-5mg5mg£322.00
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TAR-T15945-1mL1 mL * 10 mM (in DMSO)£335.00
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TAR-T15945-10mg10mg£495.00
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TAR-T15945-25mg25mg£760.00
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TAR-T15945-50mg50mg£1,026.00
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Quantity:
TAR-T15945-100mg100mg£1,340.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively). It is a potential treatment for Duchene Muscular Dystrophy (DMD).
CAS:
2095128-17-7
Formula:
C25H27F3N2O4
Molecular Weight:
476.496
Pathway:
DNA Damage/DNA Repair; Metabolism
Purity:
0.9883
SMILES:
C[C@H](CCCOc1ccccc1Cn1c(C)cnc1-c1ccc(OC(F)(F)F)cc1)CC(O)=O
Target:
PPAR

References

1. Lagu B, et al. Selective PPAR? Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD). ACS Med Chem Lett. 2018 Jul 31;9(9):935-940.